09/05 - 20:00
09/05 - 20:00
09/05 - 20:00
09/05 - 23:00
09/05 - 23:00
09/05 - 23:00
10/05 - 19:30
10/05 - 19:45
10/05 - 20:00
10/05 - 20:00
10/05 - 20:00
09/05 - 20:00
09/05 - 20:00
09/05 - 20:00
09/05 - 23:00
09/05 - 23:00
09/05 - 23:00
10/05 - 19:30
10/05 - 19:45
10/05 - 20:00
10/05 - 20:00
10/05 - 20:00
09/05 - 23:00
| 09-05 | 23:00 | Belgrano |  | vs |  | Delfín SC | Grp.C | 1.69 | 3.56 | 5.22 | |
| 10-05 | 01:00 | Red Bull Bragantino |  | vs |  | Racing Club | Grp.H | 2.09 | 3.50 | 3.32 | h2h |
| 10-05 | 03:00 | Universidad Catolica |  | vs |  | Unión La Calera | Grp.B | h2h | |||
| 10-05 | 03:00 | Deportivo Garcilaso |  | vs |  | Lanús | Grp.G | 2.67 | 3.28 | 2.57 | h2h |
| 09-05 | 23:00 | Liverpool Montevideo |  | vs |  | Palmeiras | Grp.F | 7.21 | 4.20 | 1.48 | |
| 09-05 | 23:00 | San Lorenzo |  | vs |  | Independiente del Valle | Grp.F | 2.20 | 3.25 | 3.80 | |
| 10-05 | 01:00 | The Strongest |  | vs |  | Estudiantes | Grp.C | 1.64 | 4.05 | 5.20 | h2h |
| 10-05 | 01:00 | Colo-Colo |  | vs |  | Fluminense | Grp.A | 2.29 | 3.25 | 3.26 | h2h |
| 09-05 | 20:00 | Bayer Leverkusen |  | 2-2 |  | Roma | SF | ||||
| 09-05 | 20:00 | Atalanta |  | 3-0 |  | Marseille | SF |
| 10-05 | 19:45 | Frosinone |  | vs |  | Internazionale | D36 | 5.28 | 4.50 | 1.66 | |
| 09-05 | 20:00 | Olympiacos |  | 2-0 |  | Aston Villa | SF |
| 09-05 | 19:00 | Al-Akhdoud |  | 2-3 |  | Al Nassr | D31 |
| 10-05 | 20:00 | Alavés |  | vs |  | Girona | D35 | 3.78 | 3.71 | 2.08 | |
| 10-05 | 19:30 | FC Augsburg |  | vs |  | Stuttgart | D33 | 3.94 | 4.36 | 1.88 | |
| 10-05 | 20:00 | Brest |  | vs |  | Stade de Reims | D33 | 1.77 | 4.20 | 4.71 | |
| 10-05 | 20:00 | Nice |  | vs |  | Le Havre | D33 | 1.58 | 4.35 | 6.47 | |
